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21141

Toltrazuril 5% 200ml.

Toltrazuril - Toltrazuril is the result of extensive research efforts to help treat EPM (equine protozoal myeloencephalitis) and coccidiosis in puppies and kittens.

$129.99
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Toltrazuril is the result of extensive research efforts to help treat EPM (equine protozoal myeloencephalitis), which causes a multitude of effects that manifest in a variety of symptoms. Our solution represents a new standard in coccidiosis control, belonging to the chemical group of symmetric triazinons not related to any other anticoccidial drug currently in use in veterinary medicine. Our 5% solution affects all intracellular structures of the one-celled protozoan parasite called Sarcocystis neurona.

Our Toltrazuril 5% solution is suitable for both therapy and metaphylaxis, and acts as an effective tool for controlling coccidia-related problems. By damaging the intracellular developmental stages of Coccidia, toltraturazil affects schizonts, microgametes, and macrogametes without damaging the cell tissue of the host animal. Findings from studies suggest the drug interferes with the division of the nucleus and the activity of mitochondria, which is responsible for respiratory metabolism in the parasite. In the magrometes, toltrazuril damages wall-forming bodies, and in all intracellular developmental stages, severe vacuolisation occurs due to inflation of the endoplasmatic reticulum. Toltrazuril does not interfere with immune development, and usually does not require follow-up treatment, even in advanced infections (after three to five days). However, the efficacy of the drug is independent from the severity of the infection.

Species: Horses, Dogs, Cats, Camels, Alpacas, & Pigeons 

FEATURES / BENEFITS

-prevents and reduces the severity of lesions

-stops oocyst shedding

-improves growth rate

-improves feed conversion

SPECIFICATIONS

DO NOT use the 2.5% solution sold as a pigeon remedy, as it can be caustic to the mucus membranes of cats.

DO NOT use this drug in pregnant cats as the teratogenic effects of this drug has not been adequately researched as of now.

INSTRUCTIONS

SHAKE WELL. Oral administration of 0.4ml per pound. Examples: 1000 lb. horse – 400ml. 10 lb. dog – 4ml. Preferred treatment is every four days for seven doses, then once per month thereafter OR upon advice from your veterinarian.

FOR USE WITH CATS:

The dose of Toltrazuril 5% suspension is 20 mg/kg, or 10 mg/0.2 mL per pound. In a published study, a single dose of Toltrazuril cured coccidiosis in puppies, as long as adequate environmental cleanup is performed. However, it is recommended to repeat the treatment weekly for a couple of weeks. It is CRITICAL to clean the environment to rid it of coccidia. This drug is most effective when it is used at the age of 4-6 weeks to PREVENT coccidia infection in kittens.

Toltrazuril is designed to dose cats before the presence of clinical signs. Most catteries have issues with coccidiosis in young kittens around 5 weeks of age, meaning treatment should be given around day 28 so as to kill the early stages of the protozoa. The treatment will not cause sloughing of the intestinal epithelial cells. The coccidiosis does a fine job of that on its own. Intestinal cells remain intact and functional while the single cell stages of the cocci are dead, as evidenced by staining techniques in studies. As Toltrazuril is cidal, kittens do not have to depend on their immune systems to eliminate the cocci as they would with a drug that only treats symptoms.

Toltrazuril
21141

Specific References

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